The definitive overview of haematology and its recent developments Haematology has advanced considerably in recent decades. As new developments emerge, there is a continuous need for an accessible and up-to-date survey for medical students, discussing the major haematological disorders, their clinical presentations, their treatments, and more. Written by specialists with an interest in medical education, Lecture Notes: Haematology is a succinct, highly illustrated student guide to the essentials of this important field. It integrates the physiological, pathological, and clinical dimensions of haematology in a single comprehensive guide, and provides medical students and early-career clinicians with the core knowledge required to succeed in the subject. The 11th edition of this guide includes updated sections and expanded chapters detailing the newest advances in the field. In this 11th edition of Lecture Notes: Haematology, readers will also find: Discussion of both pathogenesis and management of all major haematological disorders Online clinical cases with >150 multiple choice questions to allow you to test and apply your knowledge Lecture Notes: Haematology, 11th edition is a valuable resource for medical students and junior doctors looking to increase their expertise in this medical specialty.

States in American Constitutionalism: Interpretation, Authority, and Politics examines the often overlooked role that states have played in the development and maintenance of American constitutionalism by examining the purpose and effect of state resolutions on national constitutional meaning. From colonial practices through contemporary politics, subnational governments have made claims about what national constitutional provisions and principles ought to mean, fashioned political coalitions to back them, and asserted their authority to provoke constitutional settlement. Yet, this practice has been far from static. Political actors have altered the practice in response to their interpretive objectives and the political landscape of the day. States in American Constitutionalism explains both the development of the practice and the way each innovation to the practice affected subsequent iterations. Hays presents a series of case studies that explore the origins of the practice in colonial constitutionalism, its function in the early Republic, subsequent developments in antebellum and twentieth century politics, and contemporary practice in the first two decades of the twenty-first century. States in American Constitutionalism will be of great interest to students and academics interested in constitutional law and politics, political and constitutional development, and federalism.

State legislatures regularly and recurrently affect constitutional meaning. However, they do so not through legal pathways like constitutional amendment or judicial challenges but by passing resolutions that assert an interpretation different than the one prevailing nationally. These resolutions help rally popular and political resistance and, when successful, alter the wider political environment and constitutional culture. Despite the obvious importance of federalism to American constitutionalism, little is known about the political influence of states in defining the American constitutional order.

Through analysis of colonial practices, early American political thought, and case studies of state response to the Alien and Sedition Acts, the embargo crisis, federal spending on internal improvements, the national tariff, civil rights in the 1950s and 1960s, the USA PATRIOT Act, the REAL ID Act, and others, "Federal Constitutionalism" raises and answers the following questions:

• What is the origin of state participation in political constitutionalism and what function does it serve?
• How do state practices relate to Calhounian nullification and strong states rights claims?
• How has state participation changed over time as the strength of federalism fluctuated and politics nationalized?

"

Federal Constitutionalism" offers analysis at the intersection of federalism and politics in the fullness of time. In so doing, it provides much needed insight into state involvement in political constitutionalism. "

At a recent meeting to discuss the domains of cell biology, I put forth a case for the extracellular matrix, even though my argument ran the risk of falling on deaf ears. After all, the matrix is EXTRAcellular, outside the cells. In this book, however, the authors make a compelling case for the relevance of the matrix to cellular concerns. Not only are numerous cell types, including many epithelia, quite caught up in the business of manufacturing matrix components, but also most of them contain matrix molecules in exoskeletons that are attached to the plasmalemma and that organize or otherwise influence the affairs of the cyto plasm. The idea of this book is to present the extracellular matrix to cell biolo gists of all levels. The authors are active and busy investigators, recognized experts in their fields, but all were enthusiastic about the prospect of writing for this audience. The chapters are not "review" articles in the usual sense, nor are they rehashes of symposium talks; they were written specifically for this book and they present the "state of the art" in engaging style, with ample references to more technical or historical reviews. The book is rich in electron micro graphs and diagrams and for many of the latter, as well as for the design of the cover, we are indebted to Sylvia J. Keene, medical illustrator for the Department of Anatomy at Harvard Medical Scrool. We also owe special thanks to Susan G.

Detroit, Michigan, has long been recognized as a center of musical innovation and social change. Rebekah Farrugia and Kellie D. Hay draw on seven years of fieldwork to illuminate the important role that women have played in mobilizing a grassroots response to political and social pressures at the heart of Detroit's ongoing renewal and development project. Focusing on the Foundation, a women-centered hip hop collective, Women Rapping Revolution argues that the hip hop underground is a crucial site where Black women shape subjectivity and claim self-care as a principle of community organizing. Through interviews and sustained critical engagement with artists and activists, this study also articulates the substantial role of cultural production in social, racial, and economic justice efforts.

It happens in America every four decades and it is about to happen again. America's demand for change in the 2008 election will cause another of our country's periodic political makeovers. This realignment, like all others before it, will result from the coming of age of a new generation of young Americans - the Millennial Generation - and the full emergence of the Internet-based communications technology that this generation uses so well. Beginning in 2008, almost everything about American politics and government will transform - voting patterns, the fortunes of the two political parties, the issues that engage the nation, and our government and its public policy.Building on the seminal work of previous generational theorists, Morley Winograd and Michael D. Hais demonstrate and describe, for the first time, the two types of realignments - ""idealist"" and ""civic"" - that have alternated with one another throughout the nation's history. Based on these patterns, Winograd and Hais predict that the next realignment will be very different from the last one that occurred in 1968. ""Idealist"" realignments, like the one put into motion forty years ago by the Baby Boomer Generation, produce, among other things, a political emphasis on divisive social issues and governmental gridlock. ""Civic"" realignments, like the one that is coming, and the one produced by the famous GI or ""Greatest"" Generation in the 1930s, by contrast, tend to produce societal unity, increased attention to and successful resolution of basic economic and foreign policy issues, and institution-building.The authors detail the contours and causes of the country's five previous political makeovers, before delving deeply into the generational and technological trends that will shape the next. The book's final section forecasts the impact of the Millennial Makeover on the elections, issues, and public policies that will characterize America's politics in the decades ahead.

About every eight decades, coincident with the most stressful and perilous events in U.S. history--the Revolutionary and Civil Wars and the Great Depression and World War II--a new, positive, accomplished, and group-oriented "civic generation" emerges to change the course of history and remake America. The Millennial Generation (born 1982-2003) is America's newest civic generation.

In their 2008 book, "Millennial Makeover," Morley Winograd and Michael D. Hais made a prescient argument that the Millennial Generation would change American politics for good. Later that year, a huge surge of participation from young voters helped to launch Barack Obama into the White House.

Now, in "Millennial Momentum," Winograd and Hais investigate how the beliefs and practices of the Millennials are transforming other areas of American culture, from education to entertainment, from the workplace to the home, and from business to politics and government. The Millennials' cooperative ethic and can-do spirit have only just begun to make their mark, and are likely to continue to reshape American values for decades to come.

Drawing from an impressive array of demographic data, popular texts, and personal interviews, the authors show how the ethnically diverse, socially tolerant, and technologically fluent Millennials can help guide the United States to retain its leadership of the world community and the global marketplace. They also illustrate why this generation's unique blend of civic idealism and savvy pragmatism will enable us to overcome the internal culture wars and institutional malaise currently plaguing the country. "Millennial Momentum" offers a message of hope for a deeply divided nation.

This study uses the lens of history to elucidate barriers that have confounded a successful US strategy for Iran. This strategy blends pressure and engagement to overcome these barriers. Iran's perceptions and patterns have historical roots in a sense of Persian greatness, resentment of foreign influence, strategic Persian-Shiite loneliness, and the emergence of pragmatic national interest replacing revolutionary ideology. Analysis further demonstrates how Iran's unique characteristics, such as the populace and nature of the government, portend strategic vulnerabilities which can be used by US strategic planners. Recent US policies for Iran are evaluated to understand US perceptions and how these have contributed to an inability to deter Iran from developing nuclear weapons, proliferating terrorism, and destabilizing the region. A proposed strategy framework expounds upon key assumptions and identification of Iranian centers of gravity. A novel planning construct is created to develop the short- and long-term strategy for US relations with Iran. This study outlines a strategy based on potential vulnerabilities of Iran created by its history and the nature of the country itself. The short-term recommended strategy consists of a prioritized list of six components for creating pressure on Iran. The result of this pressure portends changes in Iran's behavior. Public diplomacy and a strategic communications effort are cross-cutting elements that tie together the components of the short-term strategy. Despite the proposed use of pressure, there are engagement aspects that allow exploitation of positive opportunities created by changes in Iran's behavior. The longterm strategy is comprised of a blend of changed assumptions and tailored goals implemented at a rate tied to improvements in US and Iranian relations. The strategy proposal outlined in this study should be implemented immediately to take advantage of current opportunities. Air University Press, Walker Papers No. 11

Detroit, MIchigan, has long been recognized as a center of musical innovation and social change. Rebekah Farrugia and Kellie D. Hay draw on seven years of fieldwork to illuminate the important role that women have played in mobilizing a grassroots response to political and social pressures at the heart of Detroit's ongoing renewal and development project. Focusing on the Foundation, a women-centered hip hop collective, Women Rapping Revolution argues that the hip hop underground is a crucial site where Black women shape subjectivity and claim self-care as a principle of community organizing. Through interviews and sustained critical engagement with artists and activists, this study also articulates the substantial role of cultural production in social, racial, and economic justice efforts.